Prevention of renal tubule re-absorption of radiometal (indium-111) labelled Fab fragment of a monoclonal antibody in mice by systemic administration of lysine
Identifieur interne : 000163 ( Main/Exploration ); précédent : 000162; suivant : 000164Prevention of renal tubule re-absorption of radiometal (indium-111) labelled Fab fragment of a monoclonal antibody in mice by systemic administration of lysine
Auteurs : RBID : ISTEX:259_1994_Article_BF00285590.pdfEnglish descriptors
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Abstract
Systemic administration of lysine to mice injected with indium-111-labelled Fab fragment of a monoclonal antibody has been shown to reduce renal uptake/retention of the radiometal. This treatment should be applicable to clinical immunoscintigraphy and radioimmunotherapy with radiometal-labelled antibody fragments.
DOI: 10.1007/BF00285590
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Gribben</name><affiliation wicri:level="1"><mods:affiliation>Cancer Research Laboratories, University of Nottingham, NG7 2RD, Nottingham, UK</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Cancer Research Laboratories, University of Nottingham, NG7 2RD, Nottingham</wicri:regionArea><wicri:noRegion>Nottingham</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="RBID">ISTEX:259_1994_Article_BF00285590.pdf</idno><date when="1994">1994</date><idno type="doi">10.1007/BF00285590</idno><idno type="wicri:Area/Main/Corpus">000B28</idno><idno type="wicri:Area/Main/Curation">000B28</idno><idno type="wicri:Area/Main/Exploration">000163</idno></publicationStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Amino acid</term><term>Immunoscintigraphy</term><term>Radiometal</term><term>Renal uptake</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="eng">Systemic administration of lysine to mice injected with indium-111-labelled Fab fragment of a monoclonal antibody has been shown to reduce renal uptake/retention of the radiometal. This treatment should be applicable to clinical immunoscintigraphy and radioimmunotherapy with radiometal-labelled antibody fragments.</div></front></TEI><mods xsi:schemaLocation="http://www.loc.gov/mods/v3 file:///applis/istex/home/loadistex/home/etc/xsd/mods.xsd" version="3.4" istexId="c56962f1e236db33e7c5429997c4719b58a5173f"><titleInfo lang="eng"><title>Prevention of renal tubule re-absorption of radiometal (indium-111) labelled Fab fragment of a monoclonal antibody in mice by systemic administration of lysine</title></titleInfo><name type="personal"><namePart type="given">M. V.</namePart><namePart type="family">Pimm</namePart><role><roleTerm type="text">author</roleTerm></role><affiliation>Cancer Research Laboratories, University of Nottingham, NG7 2RD, Nottingham, UK</affiliation></name><name type="personal"><namePart type="given">S. J.</namePart><namePart type="family">Gribben</namePart><role><roleTerm type="text">author</roleTerm></role><affiliation>Cancer Research Laboratories, University of Nottingham, NG7 2RD, Nottingham, UK</affiliation></name><typeOfResource>text</typeOfResource><genre>Short Communication</genre><genre>Brief Communication</genre><originInfo><publisher>Springer-Verlag, Berlin/Heidelberg</publisher><dateCreated encoding="w3cdtf">1994-03-08</dateCreated><dateValid encoding="w3cdtf">2004-08-14</dateValid><copyrightDate encoding="w3cdtf">1994</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract lang="eng">Systemic administration of lysine to mice injected with indium-111-labelled Fab fragment of a monoclonal antibody has been shown to reduce renal uptake/retention of the radiometal. This treatment should be applicable to clinical immunoscintigraphy and radioimmunotherapy with radiometal-labelled antibody fragments.</abstract><subject lang="eng"><genre>Key words</genre><topic>Immunoscintigraphy</topic><topic>Radiometal</topic><topic>Renal uptake</topic><topic>Amino acid</topic></subject><relatedItem type="series"><titleInfo type="abbreviated"><title>Eur J Nucl Med</title></titleInfo><titleInfo><title>European Journal of Nuclear Medicine</title><partNumber>Year: 1994</partNumber><partNumber>Volume: 21</partNumber><partNumber>Number: 7</partNumber></titleInfo><genre>Archive Journal</genre><originInfo><dateIssued encoding="w3cdtf">1994-07-01</dateIssued><copyrightDate encoding="w3cdtf">1994</copyrightDate></originInfo><subject usage="primary"><topic>Medicine & Public Health</topic><topic>Imaging / Radiology</topic><topic>Nuclear Medicine</topic></subject><identifier type="issn">0340-6997</identifier><identifier type="issn">Electronic: 1619-7089</identifier><identifier type="matrixNumber">259</identifier><identifier type="local">IssueArticleCount: 27</identifier><recordInfo><recordOrigin>Springer-Verlag, 1994</recordOrigin></recordInfo></relatedItem><identifier type="doi">10.1007/BF00285590</identifier><identifier type="matrixNumber">Art12</identifier><identifier type="local">BF00285590</identifier><accessCondition type="use and reproduction">MetadataGrant: OpenAccess</accessCondition><accessCondition type="use and reproduction">AbstractGrant: OpenAccess</accessCondition><accessCondition type="restriction on access">BodyPDFGrant: Restricted</accessCondition><accessCondition type="restriction on access">BodyHTMLGrant: Restricted</accessCondition><accessCondition type="restriction on access">BibliographyGrant: Restricted</accessCondition><accessCondition type="restriction on access">ESMGrant: Restricted</accessCondition><part><extent unit="pages"><start>663</start><end>665</end></extent></part><recordInfo><recordOrigin>Springer-Verlag, 1994</recordOrigin><recordIdentifier>259_1994_Article_BF00285590.pdf</recordIdentifier></recordInfo></mods></record>Pour manipuler ce document sous Unix (Dilib)
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